Klen SNPase

500 U (Cat# 108205)
Sales Price$135.00

Optimized version of Taq DNA Polymerase specially designed for DNA sequencing and SNP genotyping.

Klen SNPase DNA Polymerase is a version of Taq DNA polymerase with a special point mutation in the active site of the enzyme. The mutation leads to a higher specificity and precision of incorporating deoxy- and dideoxynucleotides.

Klen SNPase is ideal for SNP genotyping by allele-specific PCR (AS-PCR), allele-specific primer extension (AS-PEX) and mini-sequencing procedures. It is also recommended for cycle sequencing with dideoxynucleotides in automated fluorescent DNA sequencing as well as for manual DNA sequencing.

Klen SNPase enzyme has only 5'-3' polymerase activity, but the relative mutation rate is 10-15 fold lower compared to Taq DNA polymerase.

For HotStart applications, see SNPase HotStart.

  • Specially designed for DNA sequencing and SNP genotyping
  • Mutation in active site leads to higher specifity and higher precision with low mutation rate
  • High specificity and very low background in AS-PEX, AS-PCR and minisequencing
  • High fidelity incorporation of deoxy- and dideoxynucleotides
  • SNP genotyping
  • DNA sequencing
  • Minisequencing
  • Real-Time PCR with intercalating dyes
  • Next Generation Sequencing
  • 108205 - Klen SNPase, 500 units
  • 108225 - Klen SNPase, 2500 units
Klen SNPase is supplied with Incomplete Reaction Buffer (5x) for PCR and MgCl2 (100 mM).

Boca Scientific is your premiere source for high-quality, innovative solutions for Cell Biology, Molecular Biology, Immunology, genetics and other lab products and reagents. We bring leading-edge products from our own-line and around the world to laboratories in the US and Canada. Our goal is to offer excellent solutions to drive research and discoveries backed by superior customer support.

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