Cat# | 151863 |
Applications | ELISA, IHC, WB |
Antigen/Gene or Protein Targets | CYP3A5- Cytochrome P450 3A5 (EC 1.14.14.1) (niphedipine oxidase), (CYPIIIA5) (P450-PCN3) (HLp2). |
Reactivity | Human |
Relevance | This monoclonal antibody (MAb), when used in conjunction with the MAb specific to CYP3A7 clone F19 P2 H2, is able to differentiate between the CYP450 family 3 members: CYP3A5 and CYP3A7. |
Host | Mouse |
Immunogen | Ovalbumin-conjugated synthetic peptide DSRDGTLSGE (C-terminal sequence) |
Positive Control |
IHC: formalin-fixed, paraffin-embedded squamous oesophagus cancer sections Western blot: recombinant P450 |
Subclass | IgG1 kappa |
Myeloma Used | P3X63Ag8.653 |
Strain | Balb/c |
Notes | Recommended usage condition: 1/5 dilution, antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0 |
Research Area | Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism |
References |
CYP3A isoforms in Ewing's sarcoma tumors: an immunohistochemical study with clinical correlation. Europe PMC ID: 25670065 Profiling the expression of cytochrome P450 in breast cancer. Europe PMC ID: 20716162 Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers. Europe PMC ID: 16243809 Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis. Europe PMC ID: 15897573 Alzheimer's disease: a cell biological perspective. Europe PMC ID: 1589757 |
For Research Use Only
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