The ELISA-VIDITEST anti-EBNA-1 EBV IgG kit is intended for the diagnosis of EBV (Epstein-Barr virus)-induced or EBV-associated diseases, such as infectious mononucleosis, chronic active EBV infection, Burkitt’s lymphoma, carcinomas of Waldayer’s ring, opportunistic lymphomas (oligo- or polyclonal) and nasopharyngeal carcinoma. The kit may also be used for the overall characterization of the chronic fatigue syndrome and of immunodeficiency during which EBV is frequently activated.
This assay is a solid-phase immunoanalytical test. The polystyrene strips are coated with recombinant antigen that bears immunodominant epitopes of EBNA-1. The anti-EBNA-1 EBV antibodies, if present in the tested sera (plasma), bind to the immobilized antigens. The antibodies in complexes with antigens are later recognized by animal anti-human IgG antibodies labeled with horseradish peroxidase. The labeled antibodies are revealed by an enzymatic reaction with a chromogenic substrate.
Features
- Solid-phase immunoanalytical test for detection of IgG antibodies to EBV nuclear antigen-1 (EBNA-1)
- Used with human serum or plasma
- Complete panel of EBV serological markers can be examined in single dilution of sample
- High sensitivity and specificity
- Quantitative evaluation
Applications
- Diagnosis of EBV-induced or EBV-associated diseases
- Characterization of chronic fatigue syndrome, immunodeficiency and neuroinfection related to EBV
Contents
- ELISA break-away strips coated with specific recombinant antigens, 1 microplate
- Standard A, 1.3ml
- Standard B, 1.3ml
- Standard C, 1.3ml
- Standard D, 1.3ml
- Standard E, 1.3ml
- Anti-human IgG antibodies labeled with horseradish peroxidase (Px-conjugate), 13ml
- Wash buffer 10x concentrate, 125ml
- Dilution buffer, 100ml
- Chromogenic substrate (TMB substrate), 13ml
- Stop solution, 13ml