The Nisin controlled gene expression system (NICE®), developed at NIZO Food Research, NL, is a fully food-grade system used for controlled gene expression in Lactococcus Lactis. The NICE® system is advantageous in that it does not contain endotoxins, inclusion bodies, spores or extracellular proteases, and the tightly controlled gene expression allows the production of toxic proteins to take place. With this system, fermentation, scale-up and downstream processing are simple.
The NICE® Nisin kit, part of the NICE® expression system, functions by binding to the lipid A portion of bacterial lipopolysaccharides and then inducing pore formation in the membranes of cortex cells from excised sorghum roots. This kit includes 1 mg/ml pure nisin in 0.05% acetic acid.
Please note this product requires a license for commercial companies. Please contact us for licensing information.