Cat# | 152757 |
Applications | ELISA, IHC, WB, |
Antigen/Gene or Protein Targets | Spermatogenesis Associated 25 (SPATA25) |
Synonyms | Testis-specific gene 23 protein |
Reactivity | Human |
Relevance | SPATA25 (spermatogenesis-associated protein 25), also known as TSG23 (testis-specific gene 23 protein), is a 227 amino acid single-pass membrane protein that is thought to play a role in spermatogenesis. Predominantly expressed in testis, SPATA25 is found at 60-fold higher levels in adult testis than fetal testis. The gene encoding SPATA25 maps to human chromosome 20q13.12 and mouse chromosome 2 H3. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought to be important for seminal production and may be potential targets for male contraception. |
Host | Mouse |
Immunogen | Peptide Sequence – LVRSKRGQP |
Positive Control | Jurkat cell lysate |
Subclass | IgG |
Molecular Weight (kDa) | 23 |
Myeloma Used | P3X63Ag8.653 |
Strain | Balb/c |
Research Area | Developmental Biology |
Image: Immunohistochemistry was performed on formalin-fixed paraffin-embedded oesophageal cancer tissue sections using anti-SPATA25 [Z37P3H11*B2]. Nuclear staining was observed.
For Research Use Only