Search
Search
{{#data.error.root_cause}}
{{/data.error}}
{{^data.error}}
{{#texts.summary}}
[{{{type}}}] {{{reason}}}
{{/data.error.root_cause}}{{texts.summary}} {{#options.result.rssIcon}} RSS {{/options.result.rssIcon}}
{{/texts.summary}} {{#data.hits.hits}}
{{#_source.featured}}
FEATURED
{{/_source.featured}}
{{#_source.showImage}}
{{#_source.image}}
{{/_source.image}}
{{/_source.showImage}}
{{/data.hits.hits}}
{{{_source.title}}} {{#_source.showPrice}} {{{_source.displayPrice}}} {{/_source.showPrice}}
{{#_source.showLink}} {{/_source.showLink}} {{#_source.showDate}}{{{_source.displayDate}}}
{{/_source.showDate}}{{{_source.description}}}
{{#_source.additionalInfo}}{{#_source.additionalFields}} {{#title}} {{{label}}}: {{{title}}} {{/title}} {{/_source.additionalFields}}
{{/_source.additionalInfo}}Anti-IL22 [L7P2E2*B3]
(Cat#: 152862)
Description
| Cat# | 152862 |
| Applications | ELISA, FACS, WB |
| Antigen/Gene or Protein Targets | Interleukin 22 (IL22) |
| Synonyms | Cytokine Zcyto18, IL 10 related T cell derived inducible factor, IL 21, IL 22, IL D110, IL TIF, IL-10-related T-cell-derived-inducible factor, IL-22, IL-TIF, IL21, Il22, ILD110, ILTIF |
| Reactivity | Salmon and Rainbow Trout |
| Relevance | IL-22 is an α-helical cytokine that binds to a heterodimeric cell surface receptor composed of IL-10R2 and IL-22R1 subunits. IL-22R is expressed on tissue cells, and it is absent on immune cells. |
| Host | Mouse |
| Immunogen | Ovalbumin-conjugated synthetic peptide sequence located within the central region of the mature IL-22 polypeptide |
| Positive Control |
Western blot: recombinant IL22 (rIL22), gill lysates FACS: isolated leukocytes, kidney and spleen cells |
| Subclass | IgG1 kappa |
| Myeloma Used | P3X63Ag8.653 |
| Strain | Balb/c |
| Research Area | Aquaculture |
Image: Immunodetection of native IL-22 production within gill tissues after challenging with the bacterial fish pathogen Yersinia ruckeri. A: Relative expression of IL-22 in fish gill tissues as determined by qPCR. B: Immunodetection of IL-22 protein in the gill after purifying protein samples from Tri® Reagent. M: Molecular weight marker; +: Recombinant IL-22; -: Recombinant IL-2B. Fish number 1 exhibited low levels of IL-22 gene expression (A) and did not display detectable levels of IL-22 protein (B). Conversely, fish number 2 showed high levels of IL-22 gene expression (A) and produced detectable amounts of IL-22 protein (B). The MHC Class II antibody was used as a protein quality/loading control.
For Research Use Only.
