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{{/_source.additionalInfo}}Anti-Phosphotyrosine (clone PY20)
(Cat#: AS20 4378)
Description
- Immunogen: balbC mice immunized with phosphotyrosine coupled to carrier protein
- Host: Mouse
- Clonality: Monoclonal
- Purity: Immunogen affinity purified serum in PBS pH 7.4.
- Format: Liquid
- Quantity: 100 µg
- Storage: Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
- Tested applications: ELISA (ELISA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western blot (WB)
- Recommended dilutions: To be determined by end user
- Confirmed reactivity: Phosphotyrosine - not species dependent
- Not reactive in: No confirmed exceptions from predicted reactivity are currently known
- Phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine -phosphorylated proteins and the biochemical pathways in which they function.
