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Immunoassay Optimization
The CANDOR Bioscience portfolio provides specialized immunoassay optimization reagents and ELISA buffers designed to improve assay reliability, sensitivity, reproducibility, and stability.
Reduce nonspecific binding, cross-reactivities, matrix effects, HAMA and other assay interferences that can contribute to false-positive or false-negative results. CANDOR reagents also support effective surface blocking and long-term stabilization of antibodies, proteins, enzyme conjugates, and coated assay components.
- Immunoassay Optimization Buffers – multifunctional buffers and diluents. Reduce assay interference and improve reliability with specialized assay and sample diluents, including LowCross-Buffer® for minimizing nonspecific binding, cross-reactivities, and matrix effects, and Assay Defender® for reducing HAMA and other high-affinity antibody interference.
- Blockers – surface blocking reagents that Minimize nonspecific binding and background with optimized surface blocking reagents designed to improve assay sensitivity and specificity.
- Stabilizers – Protect antibodies, proteins, HRP and AP conjugates, and coated assay components during storage to preserve activity and support consistent assay performance and extended shelf life. These stabilization reagents for long-term storage of antibodies, proteins, and conjugates in solutions or on coated surfaces, preventing loss of functionality for improved assay performance.
- Starter Kits and Developer Packages - Evaluate multiple optimization reagents or identify the optimal combination for assay development and commercial immunoassay and kit production
CANDOR reagents support ELISA, lateral flow assays, Western blotting, IHC, bead-based and multiplex assays, protein arrays, Immuno-PCR, and other immunoassay workflows.
CANDOR’s immunoassay optimization reagents provide critical stability and reliability to COVID-19 assays. For serological ELISA, try 6 reagents in the COVID-19 ELISA Sampler Package including PlateBlock™, an animal-free blocker specifically designed for preventing false positives and negatives in serological ELISA.
For your rapid antigen tests, the virus-inactivation buffer SafetyTector™ S provides essential user safety measures to IVD medical devices. This extraction and dilution buffer inactivates COVID-19 in saliva specimens and nasopharyngeal swabs in immunoassays, preventing users from being infected by positive tests. SafetyTector™ S achieves complete virus inactivation without sacrificing the ability to detect the analyte.
SARS-CoV-2 Immunoassays: Interference elimination by affinity discrimination
Surface Blockers in serology: Some background about background
The challenges of serology - towards reliable SARS-CoV-2 antibody assays
Stabilization of ELISA plates – technology comparison
Specificity, positive predictive value and validation statistics in the context of CoViD-19
Also by CANDOR Bioscience: ReadyTector® All-in-One Solution for Western Blotting