CANDOR Citations

• Basile AJ, Biggerstaff BJ, Kosoy OL, et al. Removal of species constraints in antibody detection. Clin Vaccine Immunol. 2010;17(1):56-61. doi:10.1128/CVI.00291-09
• Basile A, Horiuchi K, Goodman C et al. Development of diagnostic microsphere-based immunoassays for Heartland virus. Journal of Clinical Virology. 2020:104693. doi:10.1016/j.jcv.2020.104693
• Becker M, Dulovic A, Junker D, et al. Immune response to SARS-CoV-2 variants of concern in vaccinated individuals. Nat Commun. 2021;12(1):3109. Published 2021 May 25. doi:10.1038/s41467-021-23473-6
• Boehm T, Ristl R, Joseph S et al. Metabolome and lipidome derangements during a severe mast cell activation event in a patient with indolent systemic mastocytosis. Journal of Allergy and Clinical Immunology. 2021. doi:10.1016/j.jaci.2021.03.043
• Cattepoel S, Gaida A, Kropf A, Nolte MW, Bolli R, Miescher SM. Effect of IVIG Formulation on IgG Binding to Self- and Exo- Antigens In Vitro and In Vivo. PLoS One. 2016;11(8):e0161826. Published 2016 Aug 25. doi:10.1371/journal.pone.0161826
• Comar M, Wong C, Tognon M, Butel JS. Neutralizing and IgG antibodies against simian virus 40 in healthy pregnant women in Italy. PLoS One. 2014;9(10):e110700. Published 2014 Oct 21. doi:10.1371/journal.pone.0110700
• Dingess KA, van Dam P, Zhu J, et al. Optimization of a human milk-directed quantitative sIgA ELISA method substantiated by mass spectrometry [published online ahead of print, 2021 Jun 25]. Anal Bioanal Chem. 2021;10.1007/s00216-021-03468-4. doi:10.1007/s00216-021-03468-4
• Endt K, Goepfert J, Omlin A, et al. Development and clinical testing of individual immunoassays for the quantification of serum glycoproteins to diagnose prostate cancer. PLoS One. 2017;12(8):e0181557. Published 2017 Aug 2. doi:10.1371/journal.pone.0181557
• Esnault S, Kelly EA, Johansson MW, et al. Semaphorin 7A is expressed on airway eosinophils and upregulated by IL-5 family cytokines. Clin Immunol. 2014;150(1):90-100. doi:10.1016/j.clim.2013.11.009
• Fink S, Ruoff F, Stahl A, et al. Multiplexed Serum Antibody Screening Platform Using Virus Extracts from Endemic Coronaviridae and SARS-CoV-2 [published online ahead of print, 2021 Mar 16]. ACS Infect Dis. 2021;10.1021/acsinfecdis.0c00725. doi:10.1021/acsinfecdis.0c00725
• Fischer S, Nasyrov E, Brosien M, Preissner KT, Marti HH, Kunze R. Self-extracellular RNA promotes pro-inflammatory response of astrocytes to exogenous and endogenous danger signals. J Neuroinflammation. 2021;18(1):252. Published 2021 Nov 2. doi:10.1186/s12974-021-02286-w
• Gavala ML, Kelly EA, Esnault S, et al. Segmental allergen challenge enhances chitinase activity and levels of CCL18 in mild atopic asthma. Clin Exp Allergy. 2013;43(2):187-197. doi:10.1111/cea.12032
• Ghori MT, Khan MS, Khan JA, et al. Seroprevalence and risk factors of glanders in working equines - Findings of a cross-sectional study in Punjab province of Pakistan. Acta Trop. 2017;176:134-139. doi:10.1016/j.actatropica.2017.07.031
• Hayden H, Ibrahim N, Klopf J, et al. ELISA detection of MPO-DNA complexes in human plasma is error-prone and yields limited information on neutrophil extracellular traps formed in vivo. PLoS One. 2021;16(4):e0250265. Published 2021 Apr 22. doi:10.1371/journal.pone.0250265
• Hoffmann A, Kunze R, Helluy X, et al. High-Field MRI Reveals a Drastic Increase of Hypoxia-Induced Microhemorrhages upon Tissue Reoxygenation in the Mouse Brain with Strong Predominance in the Olfactory Bulb. PLoS One. 2016;11(2):e0148441. Published 2016 Feb 10. doi:10.1371/journal.pone.0148441
• Hotop SK, Reimering S, Shekhar A, et al. Peptide microarrays coupled to machine learning reveal individual epitopes from human antibody responses with neutralizing capabilities against SARS-CoV-2 [published online ahead of print, 2022 Mar 23]. Emerg Microbes Infect. 2022;1-37. doi:10.1080/22221751.2022.2057874
• Komar N, Panella NA, Burkhalter KL. Focal amplification and suppression of West Nile virus transmission associated with communal bird roosts in northern Colorado. J Vector Ecol. 2018;43(2):220-234. doi:10.1111/jvec.12306
• Johnson D, Simmons E, Abdeen S et al. Sensitive assay design for detection of anti-drug antibodies to biotherapeutics that lack an immunoglobulin Fc domain. Sci Rep. 2021;11(1). doi:10.1038/s41598-021-95055-x
• Li J, Veltri RW, Yuan Z, Christudass CS, Mandecki W. Macrophage inhibitory cytokine 1 biomarker serum immunoassay in combination with PSA is a more specific diagnostic tool for detection of prostate cancer. PLoS One. 2015;10(4):e0122249. Published 2015 Apr 8. doi:10.1371/journal.pone.0122249
• Li Z, Wystrach L, Bernstein A et al. The tissue-renin-angiotensin-system of the human intervertebral disc. European Cells and Materials. 2020;40:115-132. doi:10.22203/ecm.v040a07
• Lucchese G, Vogelgesang A, Boesl F, et al. Anti-neuronal antibodies against brainstem antigens are associated with COVID-19. eBioMedicine. 2022;83. doi: 10.1016/j.ebiom.2022.104211
• Maritz L, Woudberg NJ, Bennett AC, et al. Validation of high-throughput, semiquantitative solid phase SARS coronavirus-2 serology assays in serum and dried blood spot matrices [published online ahead of print, 2021 Jun 11]. Bioanalysis. 2021;10.4155/bio-2021-0065. doi:10.4155/bio-2021-0065
• Muftuoglu M, Li L, Liang S, et al. Extended live-cell barcoding approach for multiplexed mass cytometry. Sci Rep. 2021;11(1):12388. Published 2021 Jun 11. doi:10.1038/s41598-021-91816-w
• Oggioni M, Mercurio D, Minuta D, et al. Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology. Sci Rep. 2021;11(1):9616. Published 2021 May 5. doi:10.1038/s41598-021-89032-7
• Peri C, Gori A, Gagni P, et al. Evolving serodiagnostics by rationally designed peptide arrays: the Burkholderia paradigm in Cystic Fibrosis. Sci Rep. 2016;6:32873. Published 2016 Sep 12. doi:10.1038/srep32873
• Pöhler A, Emrich T, Jordan G, et al. Comparison of assay formats used for the detection of pre-existing anti-drug antibodies against monoclonal antibodies. Bioanalysis . 2022:14(13). doi: 10.4155/bio-2022-0085
• Reischl S, Li L, Walkinshaw G, Flippin LA, Marti HH, Kunze R. Inhibition of HIF prolyl-4-hydroxylases by FG-4497 reduces brain tissue injury and edema formation during ischemic stroke. PLoS One. 2014;9(1):e84767. Published 2014 Jan 7. doi:10.1371/journal.pone.0084767
• Renk H, Dulovic A, Seidel A et al. Robust and durable serological response following pediatric SARS-CoV-2 infection. Nat Commun. 2022;13(1). doi:10.1038/s41467-021-27595-9
• Ryu JK, Yan Z, Montano M, et al. Fibrin drives thromboinflammation and neuropathology in COVID-19. Nature. 2024. doi: 10.1038/s41586-024-07873-4
• Sark A, Fromme M, Olejnicka B et al. The Relationship between Plasma Alpha-1-Antitrypsin Polymers and Lung or Liver Function in ZZ Alpha-1-Antitrypsin-Deficient Patients. Biomolecules. 2022;12(3):380. doi:10.3390/biom12030380
• Schmohl M, Beckert S, Joos TO, Königsrainer A, Schneiderhan-Marra N, Löffler MW. Superficial wound swabbing: a novel method of sampling and processing wound fluid for subsequent immunoassay analysis in diabetic foot ulcerations. Diabetes Care. 2012;35(11):2113-2120. doi:10.2337/dc11-2547
• Staufer K, Huber H, Zessner-Spitzenberg, J. et al. Gas6 in chronic liver disease—a novel blood-based biomarker for liver fibrosis. Cell Death Discov. 2023; 282(9). doi: 10.1038/s41420-023-01551-6
• Thirugnanasambandam I, Vucurevich T, Shelton T, et al. Assessment of Real-Time PCR Techniques for the Detection of Airborne Fungal Pathogens of Wheat: Role of DNA Extraction on Spore Quantification.  ACS Agricultural Science & Technology. 2024. doi: 10.1021/acsagscitech.4c00382
• Tognon M, Luppi M, Corallini A, et al. Immunologic evidence of a strong association between non-Hodgkin lymphoma and simian virus 40. Cancer. 2015;121(15):2618-2626. doi:10.1002/cncr.29404
• Urrutia A, Guan N, Mesa‐Ciller C, Afzal A, Davidoff O, Haase V. Inactivation of HIF‐prolyl 4‐hydroxylases 1, 2 and 3 in NG2‐expressing cells induces HIF2‐mediated neurovascular expansion independent of erythropoietin. Acta Physiologica. 2020. doi:10.1111/apha.13547
• Vonarburg C, Loetscher M, Spycher MO, et al. Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates. Respir Res. 2019;20(1):99. Published 2019 May 22. doi:10.1186/s12931-019-1057-3
• Wang B, Han P, Mo L, et al. Development and validation of a triplex assay to study an antibody cocktail against Ebola virus in cynomolgus serum [published online ahead of print, 2021 Apr 1]. Bioanalysis. 2021;10.4155/bio-2020-0298. doi:10.4155/bio-2020-0298
• Weiss-Tessbach M, Reiter B, Gludovacz E, et al. Recombinant human diamine oxidase prevents hemodynamic effects of continuous histamine infusion in guinea pigs. Inflamm. Res. 2023. doi: 10.1007/s00011-023-01783-3
• Zhang X, Chen H, Shao W, Lin Z, Melhem M, Lu S. A competitive ligand-binding assay for the detection of neutralizing antibodies against dostarlimab (TSR-042). AAPS Open. 2021;7(1). doi:10.1186/s41120-021-00039-w

• Comar M, Wong C, Tognon M, Butel JS. Neutralizing and IgG antibodies against simian virus 40 in healthy pregnant women in Italy. PLoS One. 2014;9(10):e110700. Published 2014 Oct 21. doi:10.1371/journal.pone.0110700
• Farber-Katz Brown S, Nguyen H, Mzyk P, et al. ANGPTL7 and Its Role in IOP and Glaucoma.Ophthalmol. Vis. Sci. 2024; 65(3):22. doi: 10.1167/iovs.65.3.22
• Fischer A, von Eiff C, Kuczius T, Omoe K, Peters G, Becker K. A quantitative real-time immuno-PCR approach for detection of staphylococcal enterotoxins. J Mol Med (Berl). 2007;85(5):461-469. doi:10.1007/s00109-006-0142-5
• Huang H, Silva B, Tsai S et al. Immunogenicity and Protective Activity of Pigeon Circovirus Recombinant Capsid Protein Virus-Like Particles (PiCV rCap-VLPs) in Pigeons (Columba livia) Experimentally Infected with PiCV. Vaccines (Basel). 2021;9(2):98. doi:10.3390/vaccines9020098
• Kumari S, Raina A, Chandra D, et al. Development and validation of novel kit for quantification of SARS-CoV-2 antibodies on clinical samples [published online ahead of print, 2021 Dec 14]. J Virol Methods. 2021;114423. doi:10.1016/j.jviromet.2021.114423
• Lathuilière A, Bohrmann B, Kopetzki E, et al. Genetic engineering of cell lines using lentiviral vectors to achieve antibody secretion following encapsulated implantation. Biomaterials. 2014;35(2):792-802. doi:10.1016/j.biomaterials.2013.10.026
• Mazzoni E, Di Stefano M, Fiore JR, et al. Serum IgG Antibodies from Pregnant Women Reacting to Mimotopes of Simian Virus 40 Large T Antigen, the Viral Oncoprotein. Front Immunol. 2017;8:411. Published 2017 Apr 10. doi:10.3389/fimmu.2017.00411
• Mrochen DM, Trübe P, Jorde I, Domanska G, van den Brandt C, Bröker BM. Immune Polarization Potential of the S. aureus Virulence Factors SplB and GlpQ and Modulation by Adjuvants. Front Immunol. 2021;12:642802. Published 2021 Apr 15. doi:10.3389/fimmu.2021.642802
• Nicolai O, Pötschke C, Raafat D, et al. Oxidation-Specific Epitopes (OSEs) Dominate the B Cell Response in Murine Polymicrobial Sepsis. Front Immunol. 2020;11:1570. Published 2020 Jul 31. doi:10.3389/fimmu.2020.01570
• Sark A, Fromme M, Olejnicka B et al. The Relationship between Plasma Alpha-1-Antitrypsin Polymers and Lung or Liver Function in ZZ Alpha-1-Antitrypsin-Deficient Patients. Biomolecules. 2022;12(3):380. doi:10.3390/biom12030380
• Schulz D, Grumann D, Trübe P, et al. Laboratory Mice Are Frequently Colonized with Staphylococcus aureus and Mount a Systemic Immune Response-Note of Caution for In vivo Infection Experiments. Front Cell Infect Microbiol. 2017;7:152. Published 2017 May 2. doi:10.3389/fcimb.2017.00152
• Tognon M, Corallini A, Manfrini M, et al. Specific Antibodies Reacting with SV40 Large T Antigen Mimotopes in Serum Samples of Healthy Subjects. PLoS One. 2016;11(1):e0145720. Published 2016 Jan 5. doi:10.1371/journal.pone.0145720

• Elschner MC, Scholz HC, Melzer F, et al. Use of a Western blot technique for the serodiagnosis of glanders. BMC Vet Res. 2011;7:4. Published 2011 Jan 19. doi:10.1186/1746-6148-7-4
• Mazzoni E, Di Stefano M, Fiore JR, et al. Serum IgG Antibodies from Pregnant Women Reacting to Mimotopes of Simian Virus 40 Large T Antigen, the Viral Oncoprotein. Front Immunol. 2017;8:411. Published 2017 Apr 10. doi:10.3389/fimmu.2017.00411
• Pöhlmann S, Krüger A, Hafezi W, et al. Detection systems for antibody responses against herpes B virus. Primate Biol. 2017;4(1):9-16. Published 2017 Feb 17. doi:10.5194/pb-4-9-2017
• Sinn S, Eichler M, Müller L, et al. NCO-sP(EO-stat-PO) coatings on gold sensors--a QCM study of hemocompatibility. Sensors (Basel). 2011;11(5):5253-5269. doi:10.3390/s110505253
• Tognon M, Corallini A, Manfrini M, et al. Specific Antibodies Reacting with SV40 Large T Antigen Mimotopes in Serum Samples of Healthy Subjects. PLoS One. 2016;11(1):e0145720. Published 2016 Jan 5. doi:10.1371/journal.pone.0145720

• Lee SH, Jeong S, Lee J, et al. Glycomic profiling of targeted serum haptoglobin for gastric cancer using nano LC/MS and LC/MS/MS. Mol Biosyst. 2016;12(12):3611-3621. doi:10.1039/c6mb00559d
• Park SY, Lee SH, Kawasaki N, et al. α1-3/4 fucosylation at Asn 241 of β-haptoglobin is a novel marker for colon cancer: a combinatorial approach for development of glycan biomarkers. Int J Cancer. 2012;130(10):2366-2376. doi:10.1002/ijc.26288
• Park SY, Kwak CY, Shayman JA, Kim JH. Globoside promotes activation of ERK by interaction with the epidermal growth factor receptor. Biochim Biophys Acta. 2012;1820(7):1141-1148. doi:10.1016/j.bbagen.2012.04.008
• Tzeng TF, Lu HJ, Liou SS, Chang CJ, Liu IM. Vinegar-Baked Radix Bupleuri Regulates Lipid Disorders via a Pathway Dependent on Peroxisome-Proliferator-Activated Receptor-α in High-Fat-Diet-Induced Obese Rats. Evid Based Complement Alternat Med. 2012;2012:827278. doi:10.1155/2012/827278

• Becker M, Dulovic A, Junker D, et al. Immune response to SARS-CoV-2 variants of concern in vaccinated individuals. Nat Commun. 2021;12(1):3109. Published 2021 May 25. doi:10.1038/s41467-021-23473-6
• Bruckmann C, Tamburri S, De Lorenzi V, et al. Mapping the native interaction surfaces of PREP1 with PBX1 by cross-linking mass-spectrometry and mutagenesis. Sci Rep. 2020;10(1):16809. Published 2020 Oct 8. doi:10.1038/s41598-020-74032-w
• Comar M, Wong C, Tognon M, Butel JS. Neutralizing and IgG antibodies against simian virus 40 in healthy pregnant women in Italy. PLoS One. 2014;9(10):e110700. Published 2014 Oct 21. doi:10.1371/journal.pone.0110700
• Elschner MC, Scholz HC, Melzer F, et al. Use of a Western blot technique for the serodiagnosis of glanders. BMC Vet Res. 2011;7:4. Published 2011 Jan 19. doi:10.1186/1746-6148-7-4
• Ghori MT, Khan MS, Khan JA, et al. Seroprevalence and risk factors of glanders in working equines - Findings of a cross-sectional study in Punjab province of Pakistan. Acta Trop. 2017;176:134-139. doi:10.1016/j.actatropica.2017.07.031
• Hayden H, Ibrahim N, Klopf J, et al. ELISA detection of MPO-DNA complexes in human plasma is error-prone and yields limited information on neutrophil extracellular traps formed in vivo. PLoS One. 2021;16(4):e0250265. Published 2021 Apr 22. doi:10.1371/journal.pone.0250265
• Holzer I, Machado Weber A, Marshall A, et al. GRN, NOTCH3, FN1, and PINK1 expression in eutopic endometrium - potential biomarkers in the detection of endometriosis - a pilot study [published online ahead of print, 2020 Oct 7]. J Assist Reprod Genet. 2020;10.1007/s10815-020-01905-4. doi:10.1007/s10815-020-01905-4
• Kibat J, Schirrmann T, Knape MJ, et al. Utilisation of antibody microarrays for the selection of specific and informative antibodies from recombinant library binders of unknown quality. N Biotechnol. 2016;33(5 Pt A):574-581. doi:10.1016/j.nbt.2015.12.003
• Mazzoni E, Di Stefano M, Fiore JR, et al. Serum IgG Antibodies from Pregnant Women Reacting to Mimotopes of Simian Virus 40 Large T Antigen, the Viral Oncoprotein. Front Immunol. 2017;8:411. Published 2017 Apr 10. doi:10.3389/fimmu.2017.00411
• Mouzinga FH, Lissom A, Heinzel C, et al. Saliva as a tool for SARS-CoV-2 genomic and immunological surveillance in the Republic of Congo. J Clin Images Med Case Rep. 2024; 5(6): 3094. doi: 10.52768/2766-7820/3094
• Mouzinga FH, Heinzel C, Lissom A, et al. Mucosal response of Inactivated and Recombinant COVID-19 vaccines in Congolese individuals. Immun Inflamm Dis. 2023;(11). doi: 10.1002/iid3.1116
• Mu L, Droujinine IA, Lee J, et al. Nanoelectronic Platform for Ultrasensitive Detection of Protein Biomarkers in Serum using DNA Amplification. Anal Chem. 2017;89(21):11325-11331. doi:10.1021/acs.analchem.7b02036
• Neunzehn J, Lüttenberg B, Wiesmann HP. Investigation of biomaterials by human epithelial gingiva cells: an in vitro study. Head Face Med. 2012;8:35. Published 2012 Dec 15. doi:10.1186/1746-160X-8-35
• Pisapati AV, Wang Y, Blauch ME, Wittenberg NJ, Cheng X, Zhang XF. Characterizing Single-Molecule Conformational Changes Under Shear Flow with Fluorescence Microscopy. J Vis Exp. 2020;(155):10.3791/60784. Published 2020 Jan 25. doi:10.3791/60784
• Polanski W, Enzensperger C, Reichmann H, Gille G. The exceptional properties of 9-methyl-beta-carboline: stimulation, protection and regeneration of dopaminergic neurons coupled with anti-inflammatory effects. J Neurochem. 2010;113(6):1659-1675. doi:10.1111/j.1471-4159.2010.06725.x
• Schneider H, Errede M, Ulrich N, Virgintino D, Frei K, Bertalanffy H. Impairment of Tight Junctions and Glucose Transport in Endothelial Cells of Human Cerebral Cavernous Malformations. Journal of Neuropathology & Experimental Neurology. 2011;70(6):417-429. doi:10.1097/nen.0b013e31821bc40e
• Sciacca B, François A, Klingler-Hoffmann M, et al. Radiative-surface plasmon resonance for the detection of apolipoprotein E in medical diagnostics applications. Nanomedicine. 2013;9(4):550-557. doi:10.1016/j.nano.2012.10.007
• Wang S, Cesca F, Loers G, et al. Synapsin I is an oligomannose-carrying glycoprotein, acts as an oligomannose-binding lectin, and promotes neurite outgrowth and neuronal survival when released via glia-derived exosomes. J Neurosci. 2011;31(20):7275-7290. doi:10.1523/JNEUROSCI.6476-10.2011
• Zhang Y, Bai J, Ying JY. A stacking flow immunoassay for the detection of dengue-specific immunoglobulins in salivary fluid. Lab Chip. 2015;15(6):1465-1471. doi:10.1039/c4lc01127a
• Zhang Y, Yu Y, Ying J. Multi‐Color Au/Ag Nanoparticles for Multiplexed Lateral Flow Assay Based on Spatial Separation and Color Co‐Localization. Adv Funct Mater. 2021:2109553. doi:10.1002/adfm.202109553

• Roy A, Miskinyte S, Garat A, Hovnanian A, Krzewinski-recchi M, Foulquier F. SPCA1 governs the stability of TMEM165 in Hailey-Hailey disease. Biochimie. 2020;174:159-170. doi:10.1016/j.biochi.2020.04.017

• Baek JO, Seo JW, Kwon O, Park SM, Kim CH, Kim IH. Production of human papillomavirus type 33 L1 major capsid protein and virus-like particles from Bacillus subtilis to develop a prophylactic vaccine against cervical cancer. Enzyme Microb Technol. 2012;50(3):173-180. doi:10.1016/j.enzmictec.2011.11.004
• Bonificio A, Ghartey-Tagoe E, Gallorini S, et al. Fabrication of cell culture-derived influenza vaccine dissolvable microstructures and evaluation of immunogenicity in guinea pigs. Vaccine. 2015;33(25):2930-2938. doi:10.1016/j.vaccine.2015.04.059
• Brazzoli M, Magini D, Bonci A et al. Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin. J Virol. 2015;90(1):332-344. doi:10.1128/jvi.01786-15
• Cattepoel S, Gaida A, Kropf A, Nolte MW, Bolli R, Miescher SM. Effect of IVIG Formulation on IgG Binding to Self- and Exo- Antigens In Vitro and In Vivo. PLoS One. 2016;11(8):e0161826. Published 2016 Aug 25. doi:10.1371/journal.pone.0161826
• Garcia Alonso M, Caballero ML, Umpierrez A, Lluch-Bernal M, Knaute T, Rodríguez-Pérez R. Relationships between T cell and IgE/IgG4 epitopes of the Anisakis simplex major allergen Ani s 1. Clin Exp Allergy. 2015;45(5):994-1005. doi:10.1111/cea.12474
• Harnoš J, Ryneš J, Víšková P, et al. Analysis of binding interfaces of the human scaffold protein AXIN1 by peptide microarrays. J Biol Chem. 2018;293(42):16337-16347. doi:10.1074/jbc.RA118.005127
• He L, Takahashi K, Pasic L et al. The effects of CD148 Q276P/R326Q polymorphisms in A431D epidermoid cancer cell proliferation and epidermal growth factor receptor signaling. Cancer Rep. 2021. doi:10.1002/cnr2.1566
• Hekele A, Bertholet S, Archer J, et al. Rapidly produced SAM(®) vaccine against H7N9 influenza is immunogenic in mice. Emerg Microbes Infect. 2013;2(8):e52. doi:10.1038/emi.2013.54
• Hornburg D, Kruse T, Anderl F et al. A mass spectrometry guided approach for the identification of novel vaccine candidates in gram-negative pathogens. Sci Rep. 2019;9(1). doi:10.1038/s41598-019-53493-8
• Kühbach K, Hülsemann M, Herrmann Y, et al. Application of an Amyloid Beta Oligomer Standard in the sFIDA Assay. Front Neurosci. 2016;10:8. Published 2016 Jan 29. doi:10.3389/fnins.2016.00008
• Park M, Kwon J, Shin H et al. Butyrate enhances the efficacy of radiotherapy via FOXO3A in colorectal cancer patient‑derived organoids. Int J Oncol. 2020. doi:10.3892/ijo.2020.5132
• Vonarburg C, Loetscher M, Spycher MO, et al. Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates. Respir Res. 2019;20(1):99. Published 2019 May 22. doi:10.1186/s12931-019-1057-3

Applications in Mass Cytometry

• Anandan S, Thomsen L, Gullaksen S et al. Phenotypic Characterization by Mass Cytometry of the Microenvironment in Ovarian Cancer and Impact of Tumor Dissociation Methods. Cancers (Basel). 2021;13(4):755. doi:10.3390/cancers13040755
• Behbehani GK, Thom C, Zunder ER, et al. Transient partial permeabilization with saponin enables cellular barcoding prior to surface marker staining. Cytometry A. 2014;85(12):1011-1019. doi:10.1002/cyto.a.22573
• Bengsch B, Ohtani T, Khan O, et al. Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells. Immunity. 2018;48(5):1029-1045.e5. doi:10.1016/j.immuni.2018.04.026
• Bongiovanni D, Klug M, Lazareva O et al. SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotype. Cell Death Dis. 2021;12(1). doi:10.1038/s41419-020-03333-9
• Canepa D, Casanova E, Arvaniti E et al. Identification of ALP+/CD73+ defining markers for enhanced osteogenic potential in human adipose-derived mesenchymal stromal cells by mass cytometry. Stem Cell Res Ther. 2021;12(1). doi:10.1186/s13287-020-02044-4
• Charmsaz S, Gross N, Jaffee E, Ho WJ. A global live cell barcoding approach for multiplexed mass cytometry profiling of mouse tumors [published online ahead of print, 2021 Mar 9]. JCI Insight. 2021;143283. doi:10.1172/jci.insight.143283
• Chevrier S, Levine JH, Zanotelli VRT, et al. An Immune Atlas of Clear Cell Renal Cell Carcinoma. Cell. 2017;169(4):736-749.e18. doi:10.1016/j.cell.2017.04.016
• Davis Z, Felices M, Lenvik T, et al. Low-density PD-1 expression on resting human natural killer cells is functional and upregulated after transplantation. Blood Adv. 2021;5(4):1069-1080. doi:10.1182/bloodadvances.2019001110
• De Jong SE, van Unen V, Manurung MD, et al. Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity [published online ahead of print, 2021 Apr 22]. Nat Immunol. 2021;10.1038/s41590-021-00911-7. doi:10.1038/s41590-021-00911-7
• Gubin MM, Esaulova E, Ward JP, et al. High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy [published correction appears in Cell. 2018 Nov 15;175(5):1443]. Cell. 2018;175(4):1014-1030.e19. doi:10.1016/j.cell.2018.09.030
• Guo N, Jia L, Out-Luiting C et al. Mass Cytometric Analysis of Early-Stage Mycosis Fungoides. Cells. 2022;11(7):1062. doi:10.3390/cells11071062
• Han G, Chen SY, Gonzalez VD, Zunder ER, Fantl WJ, Nolan GP. Atomic mass tag of bismuth-209 for increasing the immunoassay multiplexing capacity of mass cytometry. Cytometry A. 2017;91(12):1150-1163. doi:10.1002/cyto.a.23283
• Hansmann L, Blum L, Ju CH, Liedtke M, Robinson WH, Davis MM. Mass cytometry analysis shows that a novel memory phenotype B cell is expanded in multiple myeloma. Cancer Immunol Res. 2015;3(6):650-660. doi:10.1158/2326-6066.CIR-14-0236-T
• Hartmann FJ, Babdor J, Gherardini PF, et al. Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy. Cell Rep. 2019;28(3):819-831.e4. doi:10.1016/j.celrep.2019.06.049
• Kleinsteuber K, Corleis B, Rashidi N, et al. Standardization and quality control for high-dimensional mass cytometry studies of human samples. Cytometry A. 2016;89(10):903-913. doi:10.1002/cyto.a.22935
• Kothari H, Williams C, McSkimming C et al. Identification of human immune cell subtypes most responsive to IL-1β–induced inflammatory signaling using mass cytometry. Sci Signal. 2021;14(673):eabc5763. doi:10.1126/scisignal.abc5763
• Kusi M, Zand M, Lin L et al. 2-Hydroxyglutarate destabilizes chromatin regulatory landscape and lineage fidelity to promote cellular heterogeneity. Cell Rep. 2022;38(2):110220. doi:10.1016/j.celrep.2021.110220
• Lehmann M, Allers K, Heldt C, et al. Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells [published online ahead of print, 2021 Aug 21]. Mucosal Immunol. 2021;1-12. doi:10.1038/s41385-021-00437-z
• Levine LS, Hiam-Galvez KJ, Marquez DM, et al. Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response [published online ahead of print, 2021 Mar 6]. Immunity. 2021;S1074-7613(21)00084-4. doi:10.1016/j.immuni.2021.02.018
• Liu X, Lv J, Wang H, Zheng Y, Su W. Functional analysis of human circulating immune cells based on high-dimensional mass cytometry. STAR Protoc. 2022;3(2):101310. doi:10.1016/j.xpro.2022.101310
• Lun XK, Sheng K, Yu X, et al. Signal amplification by cyclic extension enables high-sensitivity single-cell mass cytometry. Nat Biotechnol.  2024. doi: 10.1038/s41587-024-02316-x
• Ma T, Luo X, George AF, et al. HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread. Elife. 2020;9:e55487. Published 2020 May 26. doi:10.7554/eLife.55487
• Muftuoglu M, Li L, Liang S, et al. Extended live-cell barcoding approach for multiplexed mass cytometry. Sci Rep. 2021;11(1):12388. Published 2021 Jun 11. doi:10.1038/s41598-021-91816-w
• O'Boyle KC, Ohtani T, Manne S, et al. Exploration of T-Cell Diversity Using Mass Cytometry. Methods Mol Biol. 2020;2111:1-20. doi:10.1007/978-1-0716-0266-9_1
• Palii CG, Cheng Q, Gillespie MA, et al. Single-Cell Proteomics Reveal that Quantitative Changes in Co-expressed Lineage-Specific Transcription Factors Determine Cell Fate. Cell Stem Cell. 2019;24(5):812-820.e5. doi:10.1016/j.stem.2019.02.006
• Park C, Ponath G, Levine-Ritterman M, et al. The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions. Acta Neuropathol Commun. 2019;7(1):130. Published 2019 Aug 12. doi:10.1186/s40478-019-0779-2
• Phongpreecha T, Fernandez R, Mrdjen D et al. Single-cell peripheral immunoprofiling of Alzheimer’s and Parkinson’s diseases. Sci Adv. 2020;6(48):eabd5575. doi:10.1126/sciadv.abd5575
• Piñol-Jurado P, Verdú-Díaz J, Fernández-Simón, et al. Imaging mass cytometry analysis of Becker muscular dystrophy muscle samples reveals different stages of muscle degeneration. Sci Rep. 2024; 3365(14). doi: 10.1038/s41598-024-51906-x
• Raju R, Chau D, Cho DS, Park Y, Verfaillie CM, Hu WS. Cell Expansion During Directed Differentiation of Stem Cells Toward the Hepatic Lineage. Stem Cells Dev. 2017;26(4):274-284. doi:10.1089/scd.2016.0119
• Roussel M, Ferrant J, Reizine F, et al. Comparative immune profiling of acute respiratory distress syndrome patients with or without SARS-CoV2 infection. Cell Rep Med. 2021:100291. doi:10.1016/j.xcrm.2021.100291
• Shen C, Li Y, Wang B. et al. HTLV-1 infection of donor-derived T cells might promote acute graft-versus-host disease following liver transplantation. Nat Commun. 2022;13:7368. doi: doi.org/10.1038/s41467-022-35111-w
• Van Elsas M, Kleinovink J, Moerland M et al. Host genetics and tumor environment determine the functional impact of neutrophils in mouse tumor models. J Immunother Cancer. 2020;8(2):e000877. doi:10.1136/jitc-2020-000877
• Vivanco Gonzalez N, Oliveria J, Tebaykin D et al. An optimized protocol for phenotyping human granulocytes by mass cytometry. STAR Protoc. 2022;3(2):101280. doi:10.1016/j.xpro.2022.101280
• McClellan, B., Alghamri, M., Thalla, R., Lowenstein, P. and Castro, M., 2022. Murine brain tumor microenvironment immunophenotyping using mass cytometry. STAR Protocols, 3(2), p.101357.doi:10.1016/j.xpro.2022.101357

Other Applications

• Basile A, Horiuchi K, Goodman C et al. Development of diagnostic microsphere-based immunoassays for Heartland virus. Journal of Clinical Virology. 2020:104693. doi:10.1016/j.jcv.2020.104693
• Basile AJ, Horiuchi K, Panella AJ, et al. Multiplex microsphere immunoassays for the detection of IgM and IgG to arboviral diseases. PLoS One. 2013;8(9):e75670. Published 2013 Sep 25. doi:10.1371/journal.pone.0075670
• Burns TJ, Frei AP, Gherardini PF, et al. High-throughput precision measurement of subcellular localization in single cells. Cytometry A. 2017;91(2):180-189. doi:10.1002/cyto.a.23054
• Danielli SG, Porpiglia E, De Micheli AJ, et al. Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance. Science Advances. 2023; 9(6). doi: doi.org/10.1126/sciadv.ade9238
• Greenbaum S, Averbukh I, Soon E, et al. A spatially resolved timeline of the human maternal-fetal interface. Nature. 2023;619(7970):595-605. doi: 10.1038/s41586-023-06298-9
• Lin JR, Chen YA, Campton D, et al. High-plex immunofluorescence imaging and traditional histology of the same tissue section for discovering image-based biomarkers. Nat Cancer. 2023. doi: 10.1038/s43018-023-00576-1
• Mantel N, Piras-Douce F, Chautard E, Marcos-Lopez E, et al. Cynomolgus macaques as a translational model of human immune responses to yellow fever 17D vaccination. J Virol. 2024. doi: 10.1128/jvi.01516-23
• Majewska J, Agrawal A, Mayo A, et al. p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells. Nat Cell Biol. 2024. doi: 10.1038/s41556-024-01465-0
• McCaffrey E, Donato M, Keren L et al. The immunoregulatory landscape of human tuberculosis granulomas. Nat Immunol. 2022. doi:10.1038/s41590-021-01121-x
• Müller L, Kannenberg J, et al. Comparison of the measured values of quantitative SARS-CoV-2 spike antibody assays. Journal of Clinical Virology. 2022:105269. doi: 10.1016/j.jcv.2022.105269
• Rahim MK, Okholm TL, Jones KB, et al. Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes.Cell. 2023. doi: 10.1016/j.cell.2023.02.021
• Nilsen M, Nygaard UC, Brodin P, et al. Gut bacteria at 6 months of age are associated with immune cell status in 1-year-old children.Scand J Immunol. 2023; 00:e13346. doi: 10.1111/sji.13346
• Reiners N, Schnurra C, Trawinski H, et al. Performance of a SARS CoV-2 antibody ELISA based on simultaneous measurement of antibodies against the viral nucleoprotein and receptor-binding domain [published online ahead of print, 2021 Jun 4]. Eur J Clin Microbiol Infect Dis. 2021;1-5. doi:10.1007/s10096-021-04284-5
• Risom T, Glass D, Liu C et al. Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma. 2021. doi:10.1101/2021.01.05.425362
• Rost S, Giltnane J, Bordeaux JM, Hitzman C, Koeppen H, Liu SD. Multiplexed ion beam imaging analysis for quantitation of protein expression in cancer tissue sections [published correction appears in Lab Invest. 2017 Oct;97(10 ):1263]. Lab Invest. 2017;97(8):992-1003. doi:10.1038/labinvest.2017.50
• Sączyńska V, Florys-Jankowska K, Porębska A, Cecuda-Adamczewska V. A Novel Epitope-Blocking ELISA for Specific and Sensitive Detection of Antibodies Against h4-Subtype Influenza Virus Hemagglutinin. 2020. doi:10.21203/rs.3.rs-93360/v1
• Yu S, Di C, Chen S. Distinct immune signatures discriminate between asymptomatic and presymptomatic SARS-CoV-2^pos subjects. Cell Res. 2021. doi:10.1038/s41422-021-00562-1
• Yu S, Lin Y, Li Y, et al. Systemic immune profiling of Omicron-infected subjects inoculated with different doses of inactivated virus vaccine. CellPress. 2023; (186); 1-17. doi: 10.1016/j.cell.2023.08.033
• Zhang Q, Pan J, Xiong D, et al. Aerosolized miR-138-5p and miR-200c targets PD-L1 for lung cancer prevention. Front Immunol. 2023; 14. doi: 10.3389/fimmu.2023.1166951

• Bonificio A, Ghartey-Tagoe E, Gallorini S, et al. Fabrication of cell culture-derived influenza vaccine dissolvable microstructures and evaluation of immunogenicity in guinea pigs. Vaccine. 2015;33(25):2930-2938. doi:10.1016/j.vaccine.2015.04.059
• Dengler M, Huber H, Müller C, Zellmer A, Rauch P, Mikulits W. Accurate Determination of Soluble Axl by Enzyme-Linked Immunosorbent Assay. Assay Drug Dev Technol. 2016;14(9):543-550. doi:10.1089/adt.2016.743
• Hekele A, Bertholet S, Archer J, et al. Rapidly produced SAM(®) vaccine against H7N9 influenza is immunogenic in mice. Emerg Microbes Infect. 2013;2(8):e52. doi:10.1038/emi.2013.54
• Kumari S, Raina A, Chandra D, et al. Development and validation of novel kit for quantification of SARS-CoV-2 antibodies on clinical samples [published online ahead of print, 2021 Dec 14]. J Virol Methods. 2021;114423. doi:10.1016/j.jviromet.2021.114423
• Lobinger D, Gempt J, Sievert W et al. Potential Role of Hsp70 and Activated NK Cells for Prediction of Prognosis in Glioblastoma Patients. Front Mol Biosci. 2021;8. doi:10.3389/fmolb.2021.669366
• Moriya S, Hiramatsu K, Kimura E, Matsumoto K, Kawakita M. Construction of an Immunochromatographic Determination System forN1,N12-diacetylspermine. J Clin Lab Anal. 2014;28(6):452-460. doi:10.1002/jcla.21709
• Mourya D, Yadav P, Gurav Y et al. Crimean Congo hemorrhagic fever serosurvey in humans for identifying high-risk populations and high-risk areas in the endemic state of Gujarat, India. BMC Infect Dis. 2019;19(1). doi:10.1186/s12879-019-3740-x
• Röder M, Wiacek C, Lankamp F, Kreyer J, Weber W, Ueberham E. Improved Sensitivity of Allergen Detection by Immunoaffinity LC-MS/MS Using Ovalbumin as a Case Study. Foods. 2021;10(12):2932. doi:10.3390/foods10122932
• Safi S, Messner L, Kliebisch M,et al. Circulating Hsp70 Levels and the Immunophenotype of Peripheral Blood Lymphocytes as Potential Biomarkers for Advanced Lung Cancer and Therapy Failure after Surgery. Biomolecules. 2023;13(5):874. doi: 10.3390/biom13050874
• Sapkal G, Shete-Aich A, Jain R, et al. Development of indigenous IgG ELISA for the detection of anti-SARS-CoV-2 IgG. Indian J Med Res. 2020;151(5):444-449. doi:10.4103/ijmr.IJMR_2232_20
• Shete A, Mohandas S, Jain R, Yadav PD. A qualitative IgG ELISA for detection of SARS-CoV-2-specific antibodies in Syrian hamster serum samples. STAR Protoc. 2021;2(2):100573. doi:10.1016/j.xpro.2021.100573
• Simon D, Tascilar K, Krönke G et al. Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion. Nat Commun. 2020;11(1). doi:10.1038/s41467-020-17703-6
• Werner C, Stangl S, Salvermoser L et al. Exosomal Hsp70 in Liquid Biopsies - A Biomarker for Prediction and Response Monitoring in Cancer. 2021. doi:10.20944/preprints202105.0524.v1
• Wielkoszynski T, Moghaddam A, Bäckman A et al. Novel diagnostic ELISA test for discrimination between infections with Yersinia enterocolitica and Yersinia pseudotuberculosis. European Journal of Clinical Microbiology & Infectious Diseases. 2018;37(12):2301-2306. doi:10.1007/s10096-018-3373-9
• Winterflood CM, Ruckstuhl T, Seeger S. Fast and Sensitive Interferon-γ Assay Using Supercritical Angle Fluorescence. Biosensors (Basel). 2013;3(1):108-115. Published 2013 Feb 8. doi:10.3390/bios3010108
• Yadav PD, Ella R, Kumar S, et al. Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques. Nat Commun. 2021;12(1):1386. Published 2021 Mar 2. doi:10.1038/s41467-021-21639-w
• Yadav PD, Gurav YK, Shete AM, et al. Kinetics of viral RNA, immunoglobulin-M & G antibodies in Kyasanur forest disease. Indian J Med Res. 2019;150(2):186-193. doi:10.4103/ijmr.IJMR_1929_17

• Basile AJ, Goodman C, Horiuchi K, et al. Development and validation of an ELISA kit (YF MAC-HD) to detect IgM to yellow fever virus. J Virol Methods. 2015;225:41-48. doi:10.1016/j.jviromet.2015.08.025
• Charmsaz S, Gross N, Jaffee E, Ho WJ. A global live cell barcoding approach for multiplexed mass cytometry profiling of mouse tumors [published online ahead of print, 2021 Mar 9]. JCI Insight. 2021;143283. doi:10.1172/jci.insight.143283
• Debald M, Jin J, Linke A et al. Calponin-h2: a potential serum marker for the early detection of human breast cancer?. Tumor Biology. 2014;35(11):11121-11127. doi:10.1007/s13277-014-2419-6
• Dengler M, Huber H, Müller CJ, Zellmer A, Rauch P, Mikulits W. Accurate Determination of Soluble Axl by Enzyme-Linked Immunosorbent Assay. Assay Drug Dev Technol. 2016;14(9):543-550. doi:10.1089/adt.2016.743
• Jacobsen EM, Fabricius D, Class, M. et al. High antibody levels and reduced cellular response in children up to one year after SARS-CoV-2 infection. Nat Commun. 2022; 13. doi: doi.org/10.1038/s41467-022-35055-1
• Lobinger D, Gempt J, Sievert W et al. Potential Role of Hsp70 and Activated NK Cells for Prediction of Prognosis in Glioblastoma Patients. Front Mol Biosci. 2021;8. doi:10.3389/fmolb.2021.669366
• Muftuoglu M, Li L, Liang S, et al. Extended live-cell barcoding approach for multiplexed mass cytometry. Sci Rep. 2021;11(1):12388. Published 2021 Jun 11. doi:10.1038/s41598-021-91816-w
• Sączyńska V, Florys-Jankowska K, Porębska A, Cecuda-Adamczewska V. A Novel Epitope-Blocking ELISA for Specific and Sensitive Detection of Antibodies Against h4-Subtype Influenza Virus Hemagglutinin. 2020. doi:10.21203/rs.3.rs-93360/v1
• Simon D, Tascilar K, Krönke G et al. Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion. Nat Commun. 2020;11(1). doi:10.1038/s41467-020-17703-6
• Werner C, Stangl S, Salvermoser L et al. Exosomal Hsp70 in Liquid Biopsies - A Biomarker for Prediction and Response Monitoring in Cancer. 2021. doi:10.20944/preprints202105.0524.v1
• Yu S, Di C, Chen S. Distinct immune signatures discriminate between asymptomatic and presymptomatic SARS-CoV-2^pos subjects. Cell Res. 2021. doi:10.1038/s41422-021-00562-1