ADS Biotec Nucleic Acid HPLC Columns and Buffers

ADS Biotec offers high-performance HPLC columns and buffers for RNA, mRNA, DNA, and oligonucleotide analysis, separation, and purification. Designed for high resolution and sensitivity, these solutions support applications ranging from analytical characterization and method development to nucleic acid purification for research and therapeutic development.

RNASep™, DNASep™, OLIGOSep™, and OLIGOSep™ HC columns utilize nonporous polymeric separation technology and are compatible with most HPLC systems. A range of optimized HPLC buffers is also available to support reliable, reproducible nucleic acid separations.

ADS Biotec HPLC technology has a long history in nucleic acid research, including use in the pioneering work of Katalin Karikó and Drew Weissman on HPLC purification of modified mRNA—research that contributed to advances underlying mRNA vaccine technology and the 2023 Nobel Prize in Physiology or Medicine View the publication here

ADS Biotec has over 20 years of experience producing HPLC buffers that deliver consistent results and superior quality ensuring efficacy for downstream applications.  For information on custom buffers contact us!

Explore solutions for RNA & DNA HPLC, oligonucleotide analysis and purification, and HPLC buffers here.