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{{/_source.additionalInfo}}Cot I Human DNA, photometric
50µg (Cat#: 402007)
Description
COT I Human DNA is prepared from human male placenta DNA and is primarily used for background reduction in applications such as Microarrays and In Situ Hybridizations.
COT I Human DNA from Bioron is made in Germany and is of the highest quality. Manufactured from the precursor, male human placental genomic DNA, BIORON obtains the COT fraction by fragmentation. The product consists mainly of fast annealing repetitive elements. The COT I DNA production process has been improved to ensure a consistent size distribution from 50 to 300 base pairs. For fragment sizes in a range of > 10 kb BIORON offers bulk quantities of Human Placenta DNA (REF 401022) on request.
Tested quality
• By photometric and fluorometric methods
• Purity A260/280 > 1.6
- Acts as a blocking agent for repetitive sequences
- Decreases false positives in Microarrays, In situ hybridizations and Southern blots
- Balanced proportion of Y-chromosomal sequences
- Enriched repetitive sequences > 98%
- Reliable size distribution 50 - 300 bp
- Consistent batches
- Virus-free, phenol treated
- Filter/ Microarray hybridization assays
- In-situ hybridization (FISH)
- Single-copy-gene hybridization
- Reduction of cross hybridization
- Cot I Human DNA, 500µg
