Description
Anti-SPINK1 (hPSTI) is an antibody to human pancreatic trypsin inhibitor domain (hPSTI). It recognizes soluble hPSTI as well as hPSTI in the pSKAN phagemid pIII-hPSTI fusion protein. This antibody was developed specifically for our pSKAN Phagemid Display System, but it can also be used in other applications related to hPSTI.
Note on anti-hPST1 antibody (SPINK1):
- "About 10 percent of prostate cancer patients are SPINK1-positive and strategies to block SPINK1 signaling may have utility in this subset of patients. These studies should stimulate the development of antibody-based therapies against SPINK1 or targeting of EGFR in SPINK1-positive cancer patients," says study author Bushra Ateeq, a research fellow at the U-M Medical School.
- Antibody to Serine protease Kazal-type 1 (SPINK1; human pancreatic secretory trypsin inhibitor domain (hPSTI))
- Recognizes soluble hPSTI as well as the hPSTI in the pIII-hPSTI fusion protein of pSKAN
- Monoclonal mouse IgG (clone R XXIII)
- Reports indicate a potential of SPINK1 as an extracellular therapeutic target in prostrate cancer
- For use with our pSKAN Phagemid Display System
- Applications related to the human pancreatic secretory trypsin inhibitor (hPSTI)
- ELISA
- Western blotting
- Anti-SPINK1 (hPSTI) antibody, monoclonal mouse, 100µl