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Human Antibodies

152767 - Anti-APCDD1L [Z35P1F10*C4]

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Cat# 152767
Applications ELISA, IHC, WB
Antigen/Gene or Protein Targets Adenomatosis Polyposis Coli Down-Regulated 1-Like (APCDD1L)
Synonyms APCDD1-like, Adenomatosis polyposis coli down-regulated 1 protein-like
Reactivity Human
Relevance Adenomatosis Polyposis Coli Down-Regulated 1-Like (APCDD1L) is a negative regulator of the Wnt signaling pathway. ADCDD1L inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. It is abundantly expressed in human hair follicles and is mutated in heteditary hypotrichosis simplex (HTS).
Host Mouse
Immunogen Peptide Sequence –KRPTSYQA (immunogen peptide is identical in sheep, cow, pig, horse and chicken)
Positive Control Jurkat cell lysate
Subclass IgG
Molecular Weight (kDa) 58
Myeloma Used P3X63Ag8.653
Strain Balb/c
Research Area Cell Signaling & Signal Transduction

 

Image: Immunohistochemistry was performed on formalin-fixed paraffin-embedded on primary colorectal cancer tissue using anti-APCDD1L [Z35P1F10*C4]. Cytoplasmic staining was observed. -Antigen retrieval step was required (microwave 10 min @ 950W in 0.01M sodium citrate buffer, pH 6.0).

 

For Research Use Only.