Anti-APCDD1L [Z35P1F10*C4]

(Cat#: 152767)
Description
Cat# 152767
Applications ELISA, IHC, WB
Antigen/Gene or Protein Targets Adenomatosis Polyposis Coli Down-Regulated 1-Like (APCDD1L)
Synonyms APCDD1-like, Adenomatosis polyposis coli down-regulated 1 protein-like
Reactivity Human
Relevance Adenomatosis Polyposis Coli Down-Regulated 1-Like (APCDD1L) is a negative regulator of the Wnt signaling pathway. ADCDD1L inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. It is abundantly expressed in human hair follicles and is mutated in heteditary hypotrichosis simplex (HTS).
Host Mouse
Immunogen Peptide Sequence – KRPTSYQA (immunogen peptide is identical in sheep, cow, pig, horse and chicken)
Positive Control Jurkat cell lysate
Subclass IgG
Molecular Weight (kDa) 58
Myeloma Used P3X63Ag8.653
Strain Balb/c
Research Area Cell Signaling & Signal Transduction

Image: Immunohistochemistry was performed on formalin-fixed paraffin-embedded on primary colorectal cancer tissue using anti-APCDD1L [Z35P1F10*C4]. Cytoplasmic staining was observed. Antigen retrieval step was required (microwave 10 min @ 950W in 0.01M sodium citrate buffer, pH 6.0). 

For Research Use Only.

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