Search
Search
{{#data.error.root_cause}}
{{/data.error}}
{{^data.error}}
{{#texts.summary}}
[{{{type}}}] {{{reason}}}
{{/data.error.root_cause}}{{texts.summary}} {{#options.result.rssIcon}} RSS {{/options.result.rssIcon}}
{{/texts.summary}} {{#data.hits.hits}}
{{#_source.featured}}
FEATURED
{{/_source.featured}}
{{#_source.showImage}}
{{#_source.image}}
{{/_source.image}}
{{/_source.showImage}}
{{/data.hits.hits}}
{{{_source.title}}} {{#_source.showPrice}} {{{_source.displayPrice}}} {{/_source.showPrice}}
{{#_source.showLink}} {{/_source.showLink}} {{#_source.showDate}}{{{_source.displayDate}}}
{{/_source.showDate}}{{{_source.description}}}
{{#_source.additionalInfo}}{{#_source.additionalFields}} {{#title}} {{{label}}}: {{{title}}} {{/title}} {{/_source.additionalFields}}
{{/_source.additionalInfo}}Anti-Cytochrome P450 3A4 [F24 P2 B10]
(Cat#: 151862)
Description
| Cat# | 151862 |
| Applications | ELISA, IHC, WB |
| Antigen/Gene or Protein Targets | CYP3A4 & CYP3A5 Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine 3-monooxigenase) |
| Reactivity | Human |
| Relevance | Cytochrome P450 3A4 (CYP3A4) encodes a member of the cytochrome P450 superfamily of enzymes that are a group of heme-thiolate monooxygenases. Cytochromes P450 catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP3A4 expressed mainly in the liver and intestine oxidizes xebiotics that are then removed from the body. |
| Host | Mouse |
| Immunogen | Ovalbumin-conjugated synthetic peptide ESRDGTVSGA |
| Positive Control |
IHC: formalin-fixed, paraffin-embedded prostate cancer sections. Western blot: recombinant P450 (shown below @ 0.5 pmol per lane). Negative control: Gentest Cat. No M101b. |
| Subclass | IgG1 kappa |
| Myeloma Used | P3X63Ag8.653 |
| Recommended Growing Conditions | Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM + 60 ml Fetal Bovine Serum + 3ml L-Glutamine + 3ml of Penicillin-Streptomycin. |
| Strain | Balb/c |
| Research Area | Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism |
| References | Profiling the expression of cytochrome P450 in breast cancer. Europe PMC ID: 20716162 |
For Research Use Only
