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Human Antibodies

151863 - Anti-Cytochrome P450 3A5 [F18P3B6]

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Cat# 151863
Applications ELISA, IHC, WB
Antigen/Gene or Protein Targets CYP3A5- Cytochrome P450 3A5 (EC 1.14.14.1) (niphedipine oxidase), (CYPIIIA5) (P450-PCN3) (HLp2).
Reactivity Human
Relevance This monoclonal antibody (MAb), when used in conjunction with the MAb specific to CYP3A7 clone F19 P2 H2, is able to differentiate between the CYP450 family 3 members: CYP3A5 and CYP3A7.
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide DSRDGTLSGE (C-terminal sequence)
Positive Control IHC: formalin-fixed, paraffin-embedded squamous oesophagus cancer sections western blot: recombinant P450 (shown below @ 0.5 pmol per lane).
Subclass IgG1 kappa
Myeloma Used P3X63Ag8.653
Strain Balb/c
Notes Recommended usage condition: 1/5 dilution, antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism
References CYP3A isoforms in Ewing's sarcoma tumors: an immunohistochemical study with clinical correlation. Europe PMC ID: 25670065

Profiling the expression of cytochrome P450 in breast cancer. Europe PMC ID: 20716162

Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers. Europe PMC ID: 16243809

Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis. Europe PMC ID: 15897573

Alzheimer's disease: a cell biological perspective. Europe PMC ID: 1589757

 

For Research Use Only