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{{/_source.additionalInfo}}Anti-DRAM1 [M3-P4B4]
(Cat#: 151871)
Description
| Cat# | 151871 |
| Applications | ELISA, IHC, IF, WB |
| Antigen/Gene or Protein Targets | Damage Regulated Autophagy Modulator 1 (DRAM1) |
| Reactivity | Human |
| Relevance | DRAM1 is significantly upregulated in colorectal cancer and significantly associated with prognosis. |
| Host | Mouse |
| Immunogen | Peptide Sequence - EKDYVYHVVS (amino acids 192 - 201) |
| Positive Control |
ELISA: Peptide immunogen Western Blot: Hela cell extract (cytoplasmic fraction) IF: Hela Cells IHC: Human hepatocellular carcinoma |
| Subclass | IgG1 |
| Myeloma Used | P3X63Ag8.653 |
| Recommended Growing Conditions | Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM + 60 ml Fetal Bovine Serum plus 3ml L-Glutamine + 3ml of Penicillin -Streptomycin. |
| Strain | Balb/c |
| Research Area | Apoptosis and Programmed Cell Death, Cancer, Cardiovascular, Cell Cycle, Cell Signaling & Signal Transduction, Metabolism |
| References | The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer. Europe PMC ID: 24608339 |
Image: Immunohistochemistry was performed on formalin-fixed, paraffin-embedded tissue sections. Positive cytoplasmic staining is observed in hepatocellualr carcinoma using anti-DRAM1 antibody [M3-P4B4]. Antigen retrieval step was required (microwave 10 min @ 950W in 0.01M sodium citrate buffer, pH 6.0)
For Research Use Only
Boca Scientific is your premiere source for high-quality, innovative solutions for Cell Biology, Molecular Biology, Immunology, genetics and other lab products and reagents. We bring leading-edge products from our own-line and around the world to laboratories in the US and Canada. Our goal is to offer excellent solutions to drive research and discoveries backed by superior customer support.
