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{{/_source.additionalInfo}}Anti-SPRED1 [M23-P2G3]
(Cat#: 151873)
Description
| Cat# | 151873 |
| Applications | ELISA, IF, WB |
| Antigen/Gene or Protein Targets | Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) |
| Reactivity | Human |
| Relevance | Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. SPRED1 can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in SPRED1 can cause neurofibromatosis type 1-like syndrome (NFLS) and contribute to Legius syndrome and childhood leukemia. |
| Host | Mouse |
| Immunogen | Peptide Sequence YVPLRMCHR (amino acids 420 – 428) |
| Positive Control | ELISA- Peptide immunogen; Western Blot- Hela whole cell extract; Immunofluorescence- Hela Cells |
| Subclass | IgG1 kappa |
| Myeloma Used | P3X63Ag8.653 |
| Recommended Growing Conditions | Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM + 60 ml Fetal Bovine Serum plus 3ml L-Glutamine + 3ml of Penicillin -Streptomycin. |
| Strain | Balb/c |
| Research Area | Cancer, Cell Signaling & Signal Transduction |
For Research Use Only.
Boca Scientific is your premiere source for high-quality, innovative solutions for Cell Biology, Molecular Biology, Immunology, genetics and other lab products and reagents. We bring leading-edge products from our own-line and around the world to laboratories in the US and Canada. Our goal is to offer excellent solutions to drive research and discoveries backed by superior customer support.
