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{{/_source.additionalInfo}}Anti-TNFRSF18 (soluble form) [T10P2H9*B9]
(Cat#: 152606)
Description
| Cat# | 152606 |
| Applications | ELISA, IHC, WB |
| Antigen/Gene or Protein Targets | Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18-soluble form), GITR |
| Synonyms | Tumor Necrosis Factor Receptor Superfamily Member 18; Glucocorticoid-Induced TNFR-Related Protein; Activation-Inducible TNFR Family Receptor; AITR; GITR; TNF Receptor Superfamily Activation-Inducible Protein; CD357 Antigen; GITR-D; CD357 |
| Reactivity | Human |
| Relevance | TNFRSF18 is a type I transmembrane protein with homology to members of divergent costimulatory molecules in the TNFRSF. To date three isoforms of TNFRSF18 have been identified, including one soluble form that lacks a transmembrane domain. According to homology of the cytoplasmic domain, TNFRSF18 and other three TNFRSF members (4–1BB, CD27, and OX40) probably constitute a new subfamily as divergent costimulators. TNFRSF18 and the other subfamily members bind TRAF molecules and activate NF-KB. |
| Host | Mouse |
| Immunogen | Ovalbumin conjugated peptide - PWQQKWVQE |
| Positive Control |
IHC: formalin-fixed, paraffin-embedded breast cancer sections. Western Blot: Jurkat cell lysates |
| Subclass | IgG1 kappa |
| Molecular Weight (kDa) | 26 |
| Notes | For IHC perform antigen retrieval: microwave 10 min @ 950W in 0.01M sodium citrate buffer, pH 6.0) |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Immunology |
Image: Immunohistochemistry was performed on wax embedded human breast cancer sections using anti-TNFRSF18 (soluble form), clone T10P2H9*B9
For Research Use Only.
Boca Scientific is your premiere source for high-quality, innovative solutions for Cell Biology, Molecular Biology, Immunology, genetics and other lab products and reagents. We bring leading-edge products from our own-line and around the world to laboratories in the US and Canada. Our goal is to offer excellent solutions to drive research and discoveries backed by superior customer support.
