EpitoGen Universal COVID-19 ELISA Test

(Cat#: EPITO-UN)

At the population level, the humoral response to SARS-CoV-2 is heterogenous.  As such, the traditional antibody assay using eithe r the spike or nucleocaspid as antigens are less sensitive. Additionally, the accumulation of SARS-CoV-2 mutations will further reduce the performance of existing assays.  To overcome this challenge, EpitoGen Technology, has been developed to produce a set of unique, highly sensitive COVID-19 ELISA tests. 

EpitoGen Technology efficiently expresses short epitopes to vastly improve antibody tests. The epitope antigen (EpitoGen) is fused in the middle of an inert scaffold protein and displayed on the top of the scaffold ideally suited for a number of antigen/antibody-based assays such as ELISA and lateral flow. 

The EpitoGen Universal COVID-19 ELISA Test was designed for maximum sensitivity and specificity. The antigen consists of a set of 15 immunodominant epitopes from N, S, M, ORF3a and ORF7a viral proteins, and their corresponding major circulating mutants (79 prevalent mutations). The combinations of the epitogens in the assay offers the ability to detect the broadest range of human anti-COVID-19 antibodies. 

Linear and conformational immunodominant epitopes are used to enrich the positive signal.  High specificity is achieved as cross-reactive epitopes are eliminated.

This EpitoGen Test includes the IgG ELISA plate and dilution buffer. Other materials are to be supplied by the user.

epitogen universal elisa

Discounts are available for bulk quantities. Inquire for pricing.

Please note: This product is for research use only.


  • Efficiently expresses short epitopes to improve antibody tests
  • Combines 5 SARS-CoV-2 viral antigens in one test to boost sensitivity (S, N, M, ORF3a, and ORF7a)
  • Sensitivity enhanced by inclusion of 79 prevalent SARS-COV-2 mutations corresponding to Omicron and Delta varaints
  • Showed 99.5% accuracy and 98.5% specificity in NIBSC assessment
  • Detects antibody response to major circulating mutants of immunodominant epitopes
  • High specificity as cross-reactive epitopes are eliminated
  • Easily integrated into existing ELISA protocols  
  • Highly stable components are easy to ship and store
  • Detection of IgG antibody response to 15 epitopes from five COVID-19 viral proteins including corresponding mutants 
  • Detection of IgM and IgA to evaluate active COVID-19 infection or mucosal immunity
  • EpitoGen Universal 96 well COVID-19 IgG ELISA plate
  • Diluent
  • 44 single tests or 22 duplicate tests per plate

Boca Scientific is your premiere source for high-quality, innovative solutions for Cell Biology, Molecular Biology, Immunology, genetics and other lab products and reagents. We bring leading-edge products from our own-line and around the world to laboratories in the US and Canada. Our goal is to offer excellent solutions to drive research and discoveries backed by superior customer support.

Recently Viewed Products