shRNA Pooled Mouse Libraries

DECIPHER™ Mouse Module 1, Pathway Targets (plasmid), 200 ug (Cat# DMPAC-M1V2-P)
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Sales Price$5,000.00
Format 
Size 
Module 
Description

This off-the-shelf, ready-to-uspooled lentiviral mouse genome-wide shRNA library is usedto assay the effects of multiple constructs in one experiment.  A unique feature is the incorporation of shRNA-specific barcodes to prevent the increased variability in the data due to the direct amplification and sequencing of hairpins. Therefore, it is easy to identify enriched or depleted shRNAs in screening readouts. The 2 modules target 5000 genes with 6 shRNA per gene. Combined, they target ~10,000 genes with 6 shRNAs per gene. 
 
Module 1: Focuses on pathway targets
 
Module 2: Focuses ondisease targets
Available formats include 200 ug plasmid and pre-packaged viral libraries at 2 x 10^8 TU and 1 x 10^9 TU.

 

  • Simultaneous screening of multiple different shRNA in a target population
  • 2 different modules to allow for more targeted screens
  • Each module targets Each module targets 5,000 genes with 6 shRNA per gene.
  • Embedded shRNA barcodes eliminate the need to sequence hairpins
  • Loss-of-Function Studies 
  • Functional Genetic Screens
  • Pooled RNAi Genetic Screens
  • Identification of Novel Targets for Therapeutics
  • Biomarker Discovery and Target Validation

 

Cat #

Product Name

Module

Size

DMPAC-M1V2-P

DECIPHER™ Mouse Module 1, Pathway Targets (plasmid)

1

200 ug

DMDAC-M2V2-P

DECIPHER™ Mouse Module 2, Disease Targets (plasmid)

2

200ug

DMPAC-M1V2-V8

DECIPHER™ Mouse Module 1, Pathway Targets (virus)

1

2 x 10^8 TU

DMDAC-M2V2-V8

DECIPHER™ Mouse Module 2, Pathway Targets (virus)

2

2 x 10^8 TU

DMPAC-M1V2-V9

DECIPHER™ Mouse Module 1, Disease Targets (virus)

1

1 x 10^9 TU

DMDAC-M2V2-V9

DECIPHER™ Mouse Module 2, Disease Targets (virus)

2

2 x 10^8 TU

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