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Human Antibodies

151864 - Anti-Cytochrome P450 3A7 [F19P2H2]

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Cat# 151864
Applications ELISA, IHC, WB
Antigen/Gene or Protein Targets CYP3A7- Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)
Reactivity Human
Relevance This monoclonal antibody (MAb), when used in conjunction with the Mab specific to CYP3A5 clone F18 P3 B6, is able to differentiate between the CYP450 family 3 members: CYP3A5 and CYP3A7
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide ESRDETVSGA (C-terminal sequence)
Positive Control IHC: formalin-fixed, paraffin-embedded prostate cancer sections. Western blot: recombinant P450 (shown below @ 0.5 pmol per lane). Negative control: Gentest Cat. No M101b.
Subclass IgG1 kappa
Strain Balb/c
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism
References CYP3A isoforms in Ewing's sarcoma tumors: an immunohistochemical study with clinical correlation. Europe PMC ID: 25670065

Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers. Europe PMC ID: 16243809

Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis. Europe PMC ID: 15897573

 

Image: Immunohistochemistry: antibody staining of prostate cancer tissue

 

For Research Use Only.