Anti-8-OHdG, HRP-conjugated

(Cat#: AS15 2887-HRP)
Description
  • Immunogen: 8-hydroxy-2-deoxy Guanosine
  • Host: Mouse
  • Clonality: Monoclonal
  • Purity: Antigen affinity purified, HPR conjugated
  • Format: Liquid
  • Quantity: 100 µg
  • Storage: Store at 4°C. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
  • Tested applications: ELISA (ELISA)
  • Recommended dilutions: 1 : 1000 (ELISA)
  • Confirmed reactivity: 8-OHdG in cell culture, plasma, urine or other samples
  • 8-hydroxy-2-deoxy Guanosine (8-OHdG) is produced by the oxidative damage of DNA by reactive oxygen and nitrogen species and serves as an established marker of oxidative stress. 1-4 Hydroxylation of guanosine occurs in response to both normal metabolic processes and a variety of environmental factors (i.e., anything that increases reactive oxygen and nitrogen species). Increased levels of 8-OHdG are associated with the aging process as well as with a number of pathological conditions including cancer, diabetes, and hypertension.

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