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{{/_source.additionalInfo}}Anti-FtsH1 + FtsH5 | ATP-dependent zinc metalloprotease FtsH1 + FtsH5 (chloroplastic)
(Cat#: AS16 3930)
Description
- Immunogen: Recombinant Arabidopsis thaliana FtsH5, UniProt: O80860; TAIR: At5g42270
- Host: Rabbit
- Clonality: Polyclonal
- Purity: Serum
- Format: Lyophilized
- Quantity: 50 µl
- Reconstitution: For reconstitution add 50 µl of sterile water
- Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
- Tested applications: Western blot (WB)
- Recommended dilutions: 1 : 5000 (WB)
- Expected | apparent MW: 67.1 kD (Arabidopsis thaliana)
- Confirmed reactivity: Arabidopsis thaliana, Nicotiana tabacum, Spinacia oleracea
- Not reactive in: Chlamydomonas reinhardtii
- FtsH belong to a family of ATP dependent peptidases. Localized in a chloroplast are following isoforms: FTSH1 (synonymes AAA, FTSH, FTSH Protease 1), Ftsh2 (VAR2, VARIEGATED 2), FtsH5 (VAR1, VARIEGATED 1), FtsH6 (FTSH PROTEASE 6), FtsH7, FtsH8. FtsH9. Localized in mitochondria are following isoforms: FtsH3, FtsH4, FtsH10, FtsH11.FtsH5 (VAR1) is a component of the ATP-dependent zinc metallopeptidase. It is involved in the thylakoids biogenesis and in the repair of damaged D1 subunit of photosystem II, a process that protects against cell death under high light conditions. It forms a complex with VAR1. FtsH5 (VAR1) and FtsH1 are interchangeable in thylakoid membranes.
- Zhao et al. (2024). Psb28 protein is indispensable for stable accumulation of PSII core complexes in Arabidopsis.Plant J. 2024 May 26. doi: 10.1111/tpj.16844.
- Both FtsH5 (VAR1) and FtsH1 ahare high degree of homology therefore this antibody recognizes both proteins
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