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{{/_source.additionalInfo}}Anti-UVR8 | Ultraviolet-B receptor UVR8
(Cat#: AS22 4716)
Description
- Immunogen: KLH-conjugated peptide derived from Arabidopsis thaliana UVR8, UniProt: Q9FN03, TAIR: At5g63860
- Host: Rabbit
- Clonality: Polyclonal
- Purity: Antigen affinity purified serum, in PBS pH 7.4
- Format: Lyophilized
- Quantity: 50 µg
- Reconstitution: For reconstitution, add 50 µl, of sterile or deionized water.
- Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
- Tested applications: Western blot (WB)
- Recommended dilutions: 1 : 1000 (WB)
- Expected | apparent MW: 47.12 kDa
- Confirmed reactivity: Arabidopsis thaliana
- Not reactive in: No confirmed exceptions from predicted reactivity are currently known
- UVR8 (Ultraviolet-B receptor UVR8) is a signaling component that acts as UV-B photoreceptor and plays a key role in establishing UV-protective responses in plants. Upon UV-B irradiation, UVR8 undergoes an immediate switch from homodimer to monomer, accumulates in the nucleus, interacts with the photomorphogenic repressor COP1 and regulates the expression of the transcription factor HY5 by associating with chromatin (through histone H2B binding) in the HY5 promoter region. Involved in controlling aspects of leaf growth and morphogenesis in response to UV-B, is required for normal progression of endocycle and has a regulatory role in stomatal differentiation as well as is required for plant circadian clock response to photomorphogenic UV-B light. Promotes photosynthetic efficiency at elevated levels of UV-B. Plays a role in mediating the effects of UV-B radiation on pathogen resistance by controlling the expression of the sinapate biosynthetic pathway. Alternative names: RCC1 domain-containing protein UVR8,Protein UV-B RESISTANCE 8.
- To be added when available, antibody available in May 2023.
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