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{{/_source.additionalInfo}}Anti-KLH | Keyhole limpet hemocyanin, Biotin-conjugated (40 µg)
(Cat#: AS99 001B)
Description
- Immunogen: Purified keyhole limpet hemocyanin (KLH), whole molecule.
- Host: Rabbit
- Clonality: Polyclonal
- Purity: Immunogen affinity purified serum in PBS, pH 7.4, conjugated to biotin.
- Format: Liquid
- Quantity: 40 µg
- Storage: Store at 4°C for 12-18 months. A preservative may be added for long time storage up to 2 years.
- Tested applications: ELISA (ELISA), Immunolocalization (IL), Western blot (WB)
- Recommended dilutions: 1: 5 000 (ELISA), 1: 5 000 (WB), 1: 1000 (IL)
- Not reactive in: No confirmed exceptions from predicted reactivity are currently known
- Keyhole limpet hemocyanin (KLH) is a large cooper-containing protein consisting of subunits with MW of 400 kDa. It is found in the hemolymph of the sea mollusk Megathura crenulata. This extracellular respiratory protein has many immunostimulatory properties, including the ability to enhance the host’s immune response by interacting with T cells, monocytes, macrophages, and polymorphonuclear lymphocytes. Since its discovery, KLH has been used primarily as a carrier for vaccines and antigens and as adjuvant treatment in regimens such as antimicrobial therapy.
- Protein present in plant vascular tissue (xylem and vascular cambium) is detected by anti-KLH antibodies (Höglund et al. 2002) which might lead to false results in IL when using anti-peptide antibodies generated to KLH-conjugated peptide.
Boca Scientific is your premiere source for high-quality, innovative solutions for Cell Biology, Molecular Biology, Immunology, genetics and other lab products and reagents. We bring leading-edge products from our own-line and around the world to laboratories in the US and Canada. Our goal is to offer excellent solutions to drive research and discoveries backed by superior customer support.