Epitogen Lyme VlsE IgM ELISA Kit

Epitogen® Lyme VlsE IgM Assay: Redefining Lyme Disease Research

The VisE Assay offers novel strain identification in Lyme confirmed cases and allows for the re-evaluation of Serology-Negative, but clinically suspected cases!

VlsE is a surface lipoprotein in Borrelia burgdorferi that undergoes antigenic variation through segmental recombination with silent cassettes. This process allows the bacterium to avoid immune detection and persist in the host, creating significant variability in VlsE among different Borrelia species— which poses a significant challenge for research, diagnostics and vaccine development.

Using proprietary Epitogen® technology, EpitogenX successfully expressed 27 full-length VlsE variants representing key pathogenic species: B. burgdorferi sensu stricto, B. afzelii, B. garinii, B. mayonii, B. spielmanii, B. bissetiae, B. bavariensis, and B. valaisiana.

This expansive VlsE antigen panel is designed to advance Borrelia research, improve strain-specific diagnostics, and support accurate epidemiological tracking. Powered by the novel Epitogen® scaffold, it ensures precise antigen orientation for reliable comparison and enhanced assay performance.

Indirect ELISA kit for the measurement of Anti-Borrelia burgdorferi IgG in Citrate plasma, Heparin Plasma, Serum samples.

• Purpose: detection of total antibodies to Borrelia burgdorferi
• Reactivity: Borrelia burgdorferi
• Detection Method: Colorimetric
• Method Type: Indirect ELISA
• Analytical Method: Qualitative

Combine this Assay with the Epitogen IgG Assays to provide even deeper insights into infection stage and immune system profile - offering enhanced clarity and stronger decision-making!

These kits are currently for Research Use Only.