Anti-Staphylococcal Protein A, FITC-conjugated

(Cat#: AS20 4471)
Description
  • Immunogen: Recombinant Protein A
  • Host: Chicken
  • Clonality: Polyclonal
  • Purity: Immunogen affinity purified in PBS pH 7.2. Contains 0.075% sodium azide, coupled to immunoprecipiation gel.
  • Format: Liquid
  • Quantity: 0.5 mg
  • Storage: Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
  • Tested applications: Immunohistochemistry (IHC)
  • Expected | apparent MW: To be determined by the end user
  • Protein A is a surface protein of S. aureus which binds IgG molecules by their Fc region. In serum, the bacteria will bind IgG molecules in the wrong orientation on their surface, which hinders opsonization and phagocytosis. Mutants of S. aureus lacking protein A are more efficiently phagocytosed in vitro and mutants in infection models have diminished virulence. Due to its affinity for the Fc region of many mammalian immunoglobulins, protein A is considered a universal reagent in biochemistry and immunology.
  • Antibodies were isolated from immune eggs, affinity purified on a Protein A column and conjugated to fluoroscein isothiocyanate (FITC).

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