Search
Search
{{#data.error.root_cause}}
{{/data.error}}
{{^data.error}}
[{{{type}}}] {{{reason}}}
{{/data.error.root_cause}}
{{#data.hits.hits}}
{{#_source.featured}}
FEATURED
{{/_source.featured}}
{{#_source.showImage}}
{{#_source.image}}
{{/_source.image}}
{{/_source.showImage}}
{{/data.hits.hits}}
{{{_source.title}}} {{#_source.showPrice}} {{{_source.displayPrice}}} {{/_source.showPrice}}
{{#_source.showLink}} {{/_source.showLink}} {{#_source.showDate}}{{{_source.displayDate}}}
{{/_source.showDate}}{{{_source.description}}}
{{#_source.additionalInfo}}{{#_source.additionalFields}} {{#title}} {{{label}}}: {{{title}}} {{/title}} {{/_source.additionalFields}}
{{/_source.additionalInfo}}DriverMap™ Single-Cell AIR (scAIR) Immunophenotyping Reagent Assay
DriverMap™ scAIR TCR-Mark36 Immunophenotyping Reagent Kit (Human) (Cat#DM-SCAIR-HTR-M36-B1)
Description
Cellecta's DriverMap™ Single-Cell AIR (scAIR) Immunophenotyping Reagent Assays combine full-length T-cell receptor (TCR) or B-cell receptor (BCR) chain-pair profiling with targeted gene expression analysis to characterize individual immune cells. By linking immune receptor sequences with expression patterns of selected immunophenotyping markers, these assays help researchers investigate immune-cell identity, differentiation, activation, and disease-associated immune responses.
The TCR-Mark36 assay profiles paired TCR alpha and beta chains together with a panel of 36 T-cell immunophenotyping marker genes, while the BCR-Mark30 assay combines BCR heavy/light chain-pair analysis with 30 B-cell immunophenotyping marker genes. These targeted panels provide complementary information about receptor identity and immune-cell phenotype within the same single-cell profiling workflow.
The assays use FACS-sorted cells collected in 96-well plates, followed by multiplex reverse transcription PCR (RT-PCR) and next-generation sequencing (NGS). Well-specific barcoding enables association of receptor sequences and marker expression data with individual cells, without requiring specialized microfluidics platforms or complex split-pool barcoding procedures.
Designed for human immune-cell research, DriverMap scAIR Immunophenotyping Assays support investigations of T- and B-cell heterogeneity, immune responses, and cellular changes associated with disease or therapeutic intervention.
Required Accessory: Required for NGS Sequencing: A compatible Universal Unique Dual Index (UDI) NGS Plate must be ordered separately. Each 96-well plate provides 96 unique dual-index combinations and supports up to four indexing reactions per well.
- Integrated Receptor and Phenotype Profiling: Combines full-length TCR or BCR chain-pair sequencing with targeted immune marker expression analysis.
- TCR-Mark36 Panel: Profiles paired TCR alpha/beta chains and 36 T-cell immunophenotyping marker genes.
- BCR-Mark30 Panel: Profiles BCR heavy/light chain pairs and 30 B-cell immunophenotyping marker genes.
- Single-Cell Characterization: Associates immune receptor sequences with selected phenotypic markers from individually sorted cells.
- Streamlined Workflow: Employs 96-well plate-based multiplex RT-PCR and NGS without requiring specialized microfluidics equipment.
- HumanImmune-Cell Profiling: Designed for characterization of human T- and B-cell populations.
-
Validator Barcode Technology: Uses internal barcoded replicates to support clonotype analysis and help identify amplification and sequencing errors.
- Single-cell T- and B-cell immunophenotyping
- Immune receptor-chain pairing and clonotype characterization
- Immuno-oncology and cancer immunotherapy research
- Auto-immune and infectious disease research
- Investigation of immune-cell differentiation and activation
- Vaccine response and immune monitoring studies
- Antibody and T-cell receptor discovery research
|
Cat # |
Description |
Species |
Size |
|
DM-SCAIR-HTR-M36-B1 |
DriverMap™ scAIR TCR-Mark36 Immunophenotyping Reagent Kit (Human) |
Human |
1 kit (for 8 96-Well Plates) |
|
DM-SCAIR-MTR-B1 |
DriverMap™ scAIR TCR Chain Profiling Reagent Kit (Mouse) |
Mouse |
1 kit (for 8 96-Well Plates) |
|
DM-SCAIR-HBR-M30-B1 |
DriverMap™ scAIR BCR-Mark30 Immunophenotyping Reagent Kit (Human) |
Human |
1 kit (for 8 96-Well Plates) |
Related Categories
CRISPR Cas9- and dCas9-Expressing Cell LinesBoca Scientific is your premiere source for high-quality, innovative solutions for Cell Biology, Molecular Biology, Immunology, genetics and other lab products and reagents. We bring leading-edge products from our own-line and around the world to laboratories in the US and Canada. Our goal is to offer excellent solutions to drive research and discoveries backed by superior customer support.
