Search
Search
{{#data.error.root_cause}}
{{/data.error}}
{{^data.error}}
{{#texts.summary}}
[{{{type}}}] {{{reason}}}
{{/data.error.root_cause}}{{texts.summary}} {{#options.result.rssIcon}} RSS {{/options.result.rssIcon}}
{{/texts.summary}} {{#data.hits.hits}}
{{#_source.featured}}
FEATURED
{{/_source.featured}}
{{#_source.showImage}}
{{#_source.image}}
{{/_source.image}}
{{/_source.showImage}}
{{/data.hits.hits}}
{{{_source.title}}} {{#_source.showPrice}} {{{_source.displayPrice}}} {{/_source.showPrice}}
{{#_source.showLink}} {{/_source.showLink}} {{#_source.showDate}}{{{_source.displayDate}}}
{{/_source.showDate}}{{{_source.description}}}
{{#_source.additionalInfo}}{{#_source.additionalFields}} {{#title}} {{{label}}}: {{{title}}} {{/title}} {{/_source.additionalFields}}
{{/_source.additionalInfo}}Human Genome-Wide CRISPRa (CRISPR activator) sgRNA Library
Human Genome-Wide CRISPRa sgRNA Library (plasmid), 200ug(Cat# KAHGW-106-P)
Description
This off-the-shelf, ready-to-use human genome-wide sgRNA library is designed to activate gene expression. The CRISPRa sgRNA Library targets nearly 19,000 human protein-coding genes, with 5 sgRNAs per gene. This is the only system that enables genome-wide gain-of-function screens to identify endogenous genes that alter phenotypes when activated rather than knocked out or turned off.Unlike a CRISPR knockout, the induction is reversible as it does not alter the underlying DNA structure.This library provides a tool for identifying candidate therapeutic targets involved in the regulation of growth, differentiation, disease pathogenesis, and other biological responses. Available formats include 200 ug plasmid and pre-packaged viral libraries at 2 x 10^8 TU and 1 x 10^9 TU.
- Pooled sgRNA Library designed to work with deactivated spCas9 (dCas9) complexed with an activator to activate gene expression
- Library includes 3700 non-targeting sgRNA controls
- Targets nearly 19,000 human coding regions
- 5 sgRNA to each Gene Target
-
Targeted Gene Activation
-
Gain of Function studies
-
Functional Genetic Screening
-
Identification of Novel Targets for Therapeutics
-
Biomarker Analysis
|
|
||
|
Cat # |
Product Name |
Size |
|
KAHGW-106-P |
Human Genome-Wide CRISPRa sgRNA Library (plasmid) |
200 ug |
|
KAHGW-106-V8 |
Human Genome-Wide CRISPRa sgRNA Library (virus) |
2 x 10^8 TU |
|
KAHGW-106-V9 |
Human Genome-Wide CRISPRa sgRNA Library (virus) |
1 x 10^9 TU |
Boca Scientific is your premiere source for high-quality, innovative solutions for Cell Biology, Molecular Biology, Immunology, genetics and other lab products and reagents. We bring leading-edge products from our own-line and around the world to laboratories in the US and Canada. Our goal is to offer excellent solutions to drive research and discoveries backed by superior customer support.
